1.THE membrane protein clathrin involved in-
2.A 76 yr old has severe bleeding from peptic ulcer and dies of hypovolemic shock. The liver at autopsy displays centrilobular necrosis. Compared to viable hepatocytes the necrotic cells contains higher concentration of-
3.At autopsy the heart of a 65 yr old man weighs only 250 gms and has small right and left ventricles. The myocardium is firm with a dark chocolate brown colour throughout.coronary artery shows minimal atherosclerosis. Which of the following substance is abundant in myocardium-
4.Av 45 yr old male had history of Hepatitis B infection. On liver biopsy ,multiple councilman bodies were seen. Electrophoresis done . pattern is-
5.A 58 yr old woman with a history of hyperlipidemia and hypertension develops progressive renal artery stenosis. Over time following morphologic adaptations is shown by kidney-
6.A 30 yr old man with AIDS complains of severe pain on swallowing. Upper GI endoscopy shows hyperemic and edematous esophageal mucosa , DX-
7.Linitis plastica is seen in-
8.all are true regarding typhoid ulcer except-
9. copper is transported in plasma by-
10.gluten sensitivity is associated with-
11. positive acid Schiff macrophages seen in-
12.typical histological change seen in benign hypertension includes-
14. A 65 yr old man id discoivered to have hyperlipidemia on screening tests after a routine physical examination. Lab studies cholesterol-290mg/dl , LDL-240 mg/dl , trygly- 300 mg/dl This patient is most at risk of developing aneurysm in which of following anatomical location-
15.most common site for glomus tumor-
16.which of the following sets of components of cigarette smoke is a causal agent of coronary artery ds
17. papillary necrosis is seen in all the following excewpt-
18. an 8 year old boy presents with headaches, dizziness and malaise. He was seen for a severe sore throat 2 weeks ago. Physical examination reveals facial oedema. The BP-180/110. 24 hours urine collection demonstrates oliguria , hematuria. Microscopy shows-
19.range of micro albuminuria is-
20.most common malignant tumor of kidney-
21.True about light microscopy in minimal change disease-
22. a 10 yr old child complaints of pain and swelling of the left foot. He gives History of injury while playing. Migration of leucocytes to the site of injury is mediated by-
23. Ferruginous body is found in-
24. Phagocytosis discovered by-
25. An 87 yr old woman had a cough productive of yellowish sputum for past 3 days . on examination her tempt 37degree celcius. A chest radiograph shows bilateral patchy infiltrates. Peripheral blood smear shows leucocytosis. A week later sher is afebrile. Outcome is-
26.a patient of 46 yrs presents to you with generalised weakness and easy fatigability. He gives you a H/O working in a factory with exposure to Benzene. Dx-
27.Cytogenic study in a 40 yr old woman with follicular lymphoma demonstrate a t(14, 18) chromosomal translocation involving bcl-2 gene. Constitutive expression of the protein encoded by bcl-2 gene inhibits which of the following processes in the patient’s transformed lymphocytes-
28. carcinoma colon marker is-
29. BARSHA GUPTA, A 35 yr old woman pr3esents for gyne examination. PAP smear of cx mucosa shows’ koilocytic atypia’ characterized by perinuclear halos and wrinkled nuclei. A cervical biopsy reveals squamous cell ca . HPV test is positive.there is H/O hysterectomy. In addition to a focus of invasive carcinoma, the pathologist identifies dysplastic squamous cells occupying the entire thickness of cervical epithelium . the basal membrane is intact. Which if the following describes the cervical lesion best-
30. Criteria for staging of disease include the following except-
31.tumor containing cells of all the three germ layers is called-
32. A 68 yr old man with H/O chronic viral hepatitis has noted a 8 kg wt loss over past 6 months . an abdomen CT scan shows nodulated liver with 10 cm mass in the rt lobe. An elevation of which marker is likely to be elevated in blood-
33.gene involved in Cowden syndrome-
34.A 65 yr old man c/o muscle weakness and a dry cough for 4 months. He has smoked 2 packets of cigarettes for 40 years . a chest xray shows a 6 cm tumor. He has hypertension and hyperglycemia. Which of the following might account for the development of hyperglycemia and HT-
35. A 63yr old woman presents with a breast lump that she discovered 6days ago. A breast biopsy shows lobular carcinoma in situ. Compared to normal epithelial cells these malignant cells would most likely show decreased expression of which of the following proteins-
36.jumping gene is known as-
37.Anti apoptotic factor is-
38.Cancer cells derives energy from-
39.True about proto-oncogene are all except-
40.most common site for TB reactivation in lung is-
41.a 20year old man brought to the emergency room after rupturing his spleen in a motorcycle accident. His blood pressure on admission is- 80/60 mmHg. Analysis of arterial gasses demonstrates metabolic acidosis. The patient is most likely suffering from –
42. chicken fat appearance is seen in-
43. a 69 yrs old woman has been bedridden from a bout of viral pneumonia for past 2 weeks. Physical examination now shows some swelling and tenderness of the right leg. Which of the following terms best describes the condition involving her rt leg-
44. A 65 yr old woman complaints of 4 months history of bad breath, regurgitation of food , occasional aspiration of food and change in the voice. A barium swallow examination shows a posterior midline pouch just above cricopharyngeus. Which of the following is likely diagnosis-
45.All are the features of tumor lysis syndrome except-
46.trosseau phenomena most commonly found in-
47.Good Pasteur syndrome is an example of hypersensitivity-
48.all are the features consisting virchow’s triad except-
49.caesating granuloma is seen in all except-
50.pathognomonic cell present in pyelonephritis is-
